Below is a list of the Isleworth & Syon Headteachers.

1. H M Richards 1897-19012. W G Lipscomb 1903-19313. W T Kenwood 1903-1931
H.M. Richards (1897-1901)W G Lipscomb (1901-1903)W T Kenwood (1903-1931)
4. W B Thurston 1931-19465. A Brierly 1946-19596. G J P Courtney 1959-1976
W B Thurston (1931-1946)A Brierley (1946-1959)G J P Courtney (1959-1976)
8. R K Hands 1976-19797. J W Merrigan 1979-19849. A C Phillips 1984-1995
R K Hands (1977-1979)J Merrigan (1979-1983)A C Phillips (1984-1995)
9. R T Weeks 1996-200010. F E Ferguson 2000-present
R T Weeks (1996-2000)F E Ferguson (2000-present)